Guide Vayne build: Items, Runes and more

Guides Vayne build runes and items highest winrate 67.65%: skill priority, abilities, counters and more 2026

Vayne Runes

Precision 67.65%
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Resolve 77.96%
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
Offense
Offense
Offense
Offense
Flex
Flex
Defense
Flex
Flex

Recommended keystones Vayne rune:

Rune main Vayne

  • Precision ⇒ Lethal Tempo ⇒ Triumph ⇒ Legend: Alacrity ⇒ Coup de Grace

Rune secondary Vayne

  • Resolve ⇒ Conditioning ⇒ Overgrowth

Shards Vayne

  • Offense ⇒ Offense ⇒ Flex

Vayne Items

Starter Items Vayne

Doran's Blade
Health Potion

Summoner Spells Vayne

Tốc biến Lá chắn Tốc hành

Skill Priority Vayne

Nhào Lộn Q
Mũi Tên Bạc W
Kết Án E

Core Items Vayne

Blade of The Ruined King
Guinsoo's Rageblade

Boots Vayne

Berserker's Greaves

Fourth, Fifth, Sixth Item options Vayne

Trinity Force
Kraken Slayer
Guardian Angel
Randuin's Omen
Yun Tal Wildarrows
Lord Dominik's Regards

Items full build Vayne (30.37%)

Blade of The Ruined King
Berserker's Greaves
Guinsoo's Rageblade
Terminus
Wit's End
Jak'Sho, The Protean

Blade of The Ruined King, Berserker's Greaves, Guinsoo's Rageblade, Terminus, Wit's End, Jak'Sho, The Protean.

Vayne items high winrate (23.71%)

Blade of The Ruined King
Berserker's Greaves
Guinsoo's Rageblade
Wit's End
Randuin's Omen
Mercurial Scimitar

Blade of The Ruined King, Berserker's Greaves, Guinsoo's Rageblade, Wit's End, Randuin's Omen, Mercurial Scimitar

Options Vayne

Yun Tal Wildarrows
Berserker's Greaves
Phantom Dancer
Infinity Edge
Bloodthirster
Jak'Sho, The Protean

Yun Tal Wildarrows, Berserker's Greaves, Phantom Dancer, Infinity Edge, Bloodthirster, Jak'Sho, The Protean

Skill Order Vayne

Skill Order Vayne Vayne Skill Path